DNA Today is a multi-award winning podcast and radio show exploring how genetics impacts our health.

Host/Producer Kira Dineen interviews leaders in genetics including genetic counselors, researchers, physicians and patient advocates.

New episodes every Friday.

DNA Today is broadcast Fridays at 10:30am EST on WHUS 91.7 FM in Connecticut.

#178 Single-Cell Spatial Genomics with Vizgen

#178 Single-Cell Spatial Genomics with Vizgen

Dr. George Emanuel share about single-cell spacial genomics in this podcast episode. Dr. Emanuel is the Scientific Cofounder and Director of Technology and Partnerships at Vizgen, a biotechnology company that is dedicated to pioneering the next generation of spatially resolved transcriptomics profiling tools to provide new insight into the biological systems that underlie human health and disease. 

Spatial genomics is a new frontier in molecular biology, which aims to assay the genomic information of single cells within their native tissue environment, combining spatial transcriptomics with single-cell sequencing. This exciting technology was named Nature’s "Method of the Year 2020"!

Dr. Emanuel has spent the past decade developing high-throughput spatial profiling technologies including extending Vizgen’s MERFISH (Multiplexed Error-Robust Fluorescence in situ Hybridization) technology to profile 10,000 genes in the same sample. He received dual undergraduate degrees from the University of Colorado, and a Ph.D. in Biophysics from Harvard University.

On This Episode We Discuss:

  • Single-cell spatial genomics

  • Difference between sequencing genes and analyzing spatial gene expression

  • Insight for researchers through gene expression analysis

  • MERFISH & MERSCOPE

  • Limitations of the testing

  • Areas of research that MERFISH can be applied to

  • How can researchers get access to a MERSCOPE Platform

If you’re interested in learning more about Vizgen’s technology, visit their website to play around with the MERSCOPE Vizualizer, and check out their papers on mapping the brain  and how MERFISH was demonstrated on 10,000 genes.

Keep up to date with the latest developments at Vizgen by following them on Twitter, Facebook, and LinkedIn, and connect with our guest, Dr. George Emanuel on Linkedin!

Stay tuned for the next new episode of DNA Today on April 8, 2022 where our host, Kira Dineen, will be on the other side of the mic. She will be interviewed by James Fodor of The Science of Everything Podcast about genetic testing. New episodes are released on Fridays. In the meantime, you can binge over 175 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel.  

DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. 

See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com

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Sema4 offers an extensive portfolio of health information solutions, including pre-clinical and clinical trial support, analytics for actionable insights, and advanced sequencing services. Sema4’s family of precision oncology products and services, Sema4 Signal®, provides data-driven care solutions with advanced analytics, digital tools, and exome-based somatic and hereditary cancer genomic tests. Learn more about their mission at Sema4.com. Sema4, a patient-centered health intelligence company. 

#179 Genetic Testing with Kira Dineen

#179 Genetic Testing with Kira Dineen

#177 Whole Genome Sequencing with PerkinElmer Genomics

#177 Whole Genome Sequencing with PerkinElmer Genomics